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Evanguedes Kalapothakis Selected Research

Spider Bites (Spider Bite)

9/2021A prokaryote system optimization for rMEPLox expression: A promising non-toxic antigen for Loxosceles antivenom production.
12/2020Molecular cloning and functional characterization of recombinant Loxtox from Loxosceles similis venom.
11/2020Engineered antigen containing epitopes from Loxosceles spp. spider toxins induces a monoclonal antibody (Lox-mAb3) against astacin-like metalloproteases.
6/2014Apoptosis, mast cell degranulation and collagen breakdown in the pathogenesis of loxoscelism in subcutaneously implanted sponges.
6/2012Sponge implant in Swiss mice as a model for studying loxoscelism.
3/2003Protection against dermonecrotic and lethal activities of Loxosceles intermedia spider venom by immunization with a fused recombinant protein.

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Evanguedes Kalapothakis Research Topics

Disease

6Spider Bites (Spider Bite)
09/2021 - 03/2003
4Hemorrhage
12/2019 - 06/2012
3Infections
03/2021 - 04/2009
3Scorpion Stings
12/2016 - 01/2008
3Edema (Dropsy)
10/2015 - 08/2005
2Bites and Stings (Sting)
01/2019 - 02/2006
2Fever (Fevers)
08/2014 - 02/2006
2Aphthous Stomatitis (Aphthous Ulcer)
09/2005 - 04/2003
1Sepsis (Septicemia)
03/2021
1Neoplasms (Cancer)
10/2018
1Gas Gangrene (Gangrene, Gas)
02/2018
1Gliosis
08/2016
1Atrial Fibrillation
01/2016
1Cardiovascular Diseases (Cardiovascular Disease)
01/2016
1Tremor (Tremors)
01/2016
1Necrosis
10/2015
1Hypothermia
08/2014
1Ulcer
06/2014
1Nerve Degeneration
12/2013
1Neuroinflammatory Diseases
12/2013
1Hemolysis
11/2012
1Enterotoxemia
08/2010
1Poisoning
06/2009
1Disease Progression
04/2009
1Lithiasis
12/2008
1Pain (Aches)
12/2008
1Vomiting
02/2006
1Azotemia
02/2006
1Hematuria
02/2006
1Hemolytic Anemia
02/2006
1Disseminated Intravascular Coagulation
02/2006
1Acute Kidney Injury (Acute Renal Failure)
02/2006
1Glioma (Gliomas)
08/2005
1Wounds and Injuries (Trauma)
01/2005
1Hypoglycemia (Reactive Hypoglycemia)
03/2003
1Pancreatitis
03/2003
1Nesidioblastosis (Nesidioblastosis of Pancreas)
03/2003
1Bradycardia
01/2003
1Heart Arrest (Cardiac Arrest)
01/2003

Drug/Important Bio-Agent (IBA)

14VenomsIBA
12/2020 - 01/2003
4Antivenins (Antivenoms)IBA
09/2021 - 06/2009
3loxosceles venomIBA
09/2021 - 06/2012
2AntibodiesIBA
09/2021 - 01/2008
2EpitopesIBA
09/2021 - 01/2008
2Hyaluronoglucosaminidase (Hyaluronidase)FDA Link
01/2019 - 10/2015
2Scorpion Venoms (Scorpion Venom)IBA
12/2016 - 08/2014
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/2013 - 06/2012
2Spider Venoms (Venom, Spider)IBA
12/2013 - 08/2005
2DNA (Deoxyribonucleic Acid)IBA
01/2005 - 04/2003
1Neutralizing AntibodiesIBA
09/2021
1EnzymesIBA
12/2020
1Phospholipase DIBA
12/2020
1Peptide Hydrolases (Proteases)FDA Link
12/2019
16-chloro-2-(1-piperazinyl)pyrazine (CPP)IBA
10/2018
1Pharmaceutical PreparationsIBA
10/2018
1Calcium Channels (Calcium Channel)IBA
10/2018
1Clostridium perfringens alpha toxinIBA
02/2018
1Connexin 43 (Connexin43)IBA
08/2016
1Grammostola spatulata MTx4 proteinIBA
01/2016
1Natriuretic PeptidesIBA
01/2016
1Peptides (Polypeptides)IBA
01/2016
1CationsIBA
01/2016
1Anti-Arrhythmia AgentsIBA
01/2016
1Serine (L-Serine)FDA Link
10/2015
1Phospholipases A2 (Phospholipase A2)IBA
10/2015
1L-Amino Acid OxidaseIBA
10/2015
1Metalloproteases (Metalloproteinases)IBA
10/2015
1ProdrugsIBA
08/2014
1Dinoprostone (PGE2)FDA Link
08/2014
1Dipyrone (Metamizole)IBA
08/2014
1AntipyreticsIBA
08/2014
1CollagenIBA
06/2014
1NeurotoxinsIBA
02/2014
1Biological ProductsIBA
11/2012
1ToxoidsIBA
08/2010
1Transforming Growth Factor beta (TGF-beta)IBA
04/2009
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
04/2009
1Interleukin-10 (Interleukin 10)IBA
04/2009
1CytokinesIBA
04/2009
1Cholecalciferol (Vitamin D3)FDA Link
12/2008
1Phenobarbital (Luminal)FDA Link
12/2008
1Androgen Receptors (Androgen Receptor)IBA
12/2008
1CalciumIBA
12/2008
1Testosterone (Sustanon)FDA Link
12/2008
1Celecoxib (Celebrex)FDA Link
12/2008
1Urea (Carbamide)FDA LinkGeneric
02/2006
1NitrogenIBA
02/2006
1Serotonin Plasma Membrane Transport Proteins (Serotonin Transporter)IBA
09/2005
1Neutral RedIBA
08/2005
1Immune Sera (Antisera)IBA
03/2003

Therapy/Procedure

2Therapeutics
09/2021 - 02/2014
1Central Venous Catheters
03/2021
1Catheters
03/2021